Faʻailoga o cholestasis
O faʻailoga faʻailo o le cholestasis o loʻo pulea e le jaundice (lanu samasama o le paʻu ma fuainumera) fesoʻotaʻi ma pogisa pouliuli, nofoa suia ma le tasi gaugau (mageso).
I le tulaga o extrahepatic cholestasis, hepatomegaly (faʻateleina o le tele o le ate maitauina luga palpation o le manava), o se lapisi lapisi ma fiva e mafai ona vaʻaia e le fomaʻi i le taimi o le tino suʻesuʻega.
Faʻamoemoeina i le mafuaʻaga o le cholestasis, isi le faʻapitoa faʻapitoa faʻailoga mafai ona maua (mo se faʻataʻitaʻiga paʻu mamafa i le kanesa).
Laboratory tofotofoga o le toto faʻaalia:
-a faateleina alkaline phosphatase o le autu elemene i le faʻamaoniga o cholestasis.
-o se faʻateleina o gamma-glutamyl transpeptidase (gGT). Lenei faʻaopoopoga e le faʻapitoa mo cholestasis ma mafai ona maitauina i ate uma ma biliary faʻaletonu (ava malosi mo se faʻataʻitaʻiga)
-o se faʻateleina o le faʻatasi faʻatasi bilirubin, nafa ma jaundice
-faailoga o vitamini A, D, E, K le atoatoa
-o le faʻaititia o le prothrombin (PT) tulaga e fesoʻotaʻi ma le paʻu o le vaega V (coagulation protein) i le le lava o le hepatocellular
Ina ia iloa le mafuaʻaga o cholestasis, leO le ultrasound abdominal o le muamua-laina suʻesuʻega, o loʻo faʻaalia ai le faʻalauteleina o le sela afu i tulaga o extrahepatic cholestasis. I le tulaga o intrahepatic cholestasis, e le maua e le ultrasound manava le faʻalauteleina o le sela sela.
I le faʻamoemoe lona lua, e ono manaʻomia e le fomaʻi nisi faʻataʻitaʻiga o leitio:
- o le cholangiopancreatography (x-ray o le gaʻo gaʻo pe a uma ona faʻaaogaina se eseesega oloa)
- o le manava scan
-O se MRI (Nuclear Magnetic Resonance Imaging) o le gaʻo gaʻo
-o se endoscopy
I le leai o se le masani ai o gaʻo gaʻo faʻaalia e le ultrasound, o isi suʻesuʻega e faia e faʻailoa ai le mafuaʻaga o le cholestasis:
-faʻapitoa suʻesuʻega toto (saili mo anti-mitochondrial antibodies ma antinuclear antibodies) atonu o le faʻailoga o le muamua biliary cirrhosis.
- o se sailiga mo siama faʻatonuina mo le hepatitis mafai ona faia
Afai o nei suʻesuʻega eseese e leʻi faʻaalia mai se mafuaʻaga faʻapitoa, e ono manaʻomia se biopsy o le ate.
Tulaga faʻapitoa: cholestasis o maʻito. -E tupu soo i le taimi o le tolu masina tolu o maitaga ma o se mataʻutia i le fetus. -O le masini e fesoʻotaʻi i le faʻaputuputuina o le bile acid i le tina tina; nei sili atu gaʻo acids mafai kolosi le placenta ma aoina i le toto o le fetus. -Titia I lalo ole 1% o maitaga e afaina ile cholestasis ole maitaga [1] -O le aʻafia o cholestasis o maʻito ua faʻateleina i le mea e tupu o masaga toʻalua, oe lava poʻo aiga talaʻaga o cholestasis o maʻito -E faʻaalia ia lava e le pruritus (ogaoga le mageso) sili i alofilima ma alofivae, ae ono popole le tino atoa. I le leai o se togafitiga faʻafomaʻi, jaundice ono aliaʻe -O le faʻamaoniga e faʻamaonia e le toto suʻesuʻega suʻesuʻega faʻaalia ai le faʻaopoopoga i gaʻo gaʻo -O le lamatiaga, laʻititi mo le tina, mafai ona ogaoga mo le fetus: fetal mafatiaga ma le ono aʻafia i le vave fanauina - Togafitiga ma ursodeoxycholic acid faʻaititia ai le faʻatuputeleina o le bile acid ma pruritus -After fananau, le pruritus faasolosolo lemu mou ese ma ate gaioiga toe foi i le masani ai - E tatau ona vaʻavaʻaia i le taimi o le maʻitaga mulimuli ane. |